Hot buttons currently on the market are GLP-1 receptor agonists (GLP-1 RAs) and GLP-1 + GIP injections that work by supporting your body’s own biology. GLP-1, or glucagon-like peptide-1, is a hormone produced in the intestines that helps regulate blood sugar levels and appetite. GIP, or glucose-dependent insulinotropic polypeptide, works in tandem with GLP-1 to release insulin after eating, improve how the body uses fat, and support stable energy levels throughout the day.
GLP-1 levels naturally rise after a meal to help control appetite, but for some people, those levels can stay too low, making it harder to feel full or maintain weight loss. When that happens, the body can slip into what’s called metabolic adaptation, a state where it burns fewer calories at rest in order to store caloric energy.
By combining your body’s natural meal-time spike with a steady, therapeutic dose of GLP-1 RA or GLP-1+GIP, these medications can help regulate appetite, support fullness, and potentially reduce the body’s tendency to resist continued weight loss. Because every person’s biology is unique, dosage, side effects, and existing health conditions all require careful monitoring. Working closely with an experienced, OMA-certified practitioner is key to seeing safe, effective results.